The Top 8 Nattokinase Supplements to Boost Immunity and Lower Your Blood Pressure

If you have a history of high cholesterol and blood pressure, nattokinase supplements may help you improve your cardiovascular health.

The best nattokinase supplements can improve not only your blood pressure and cholesterol levels, but decrease the risk of a heart attack. 

What does nattokinase do?

Nattokinase is a natural enzyme found in natto, which is a traditional Japanese dish made from soybeans fermented with the bacterium Bacillus subtillis natto. Since Nattokinase is an enzyme, it breaks down fibrin – a protein that plays a role in blood clots. As such, people use the supplement to support their cardiovascular health and prevent strokes and heart attacks.

Nattokinase also offers other benefits like:

  • Improving circulation
  • Reducing inflammation
  • Boosting the immune system

Nattokinase can interact with blood thinners and other medications. If you’re considering adding this supplement to your daily intake, be sure to consult your doctor beforehand.

Here are the top 8 nattokinase supplements on the market:

Swanson Ultra Nattokinase
Doctor's Best Nattokinase
Vitacost Mega Nattokinase
Arthur Andrew Medical Nattovena Pure Nattokinase
Healthy Origins Natural Nattokinase
Nutricost Nattokinase
Source Naturals NSK-SD Nattokinase
NusaPure Nattokinase

Swanson Ultra Nattokinase 

Nattokinase 2,000 Fibrinolytic Units
Image courtesy of Swanson Vitamins’ website

Swanson Ultra Nattokinase delivers 2,000 fibrinolytic units (FU) of nattokinase per capsule, which is a high potency dose. The brand has a long-standing reputation for producing premium dietary supplements backed by rigorous quality control and testing. As this comes in capsule form, you should take the capsule with water at least two hours before or after a meal. 

Click here to buy the supplement.

Here are two public reviews:

“I recommend this product. It's working very well for me, and I plan to buy more.” - Thomas, swansonvitamins.com 
“I noticed an increase in my energy levels within a couple of days of taking this. Love the product.” - KDe1, swansonvitamins.com

Doctor’s Best Nattokinase

Image courtesy of iHerb’s website

Doctor's Best Nattokinase is committed to delivering premium supplements crafted from high-quality ingredients, and their nattokinase undergoes a meticulous extraction process to ensure purity and potency. Their supplements are also backed by rigorous testing and quality control measures. The product  is made with non-GMO, vegan ingredients and is free of gluten and artificial additives. Each capsule contains 2,000 FU, so taking one capsule each day is the proper amount.

Click here to buy the supplement.

Here are two public reviews:

“Cannot recommend this highly enough. I’ve been using this and vegenac as a combination since having covid it has made improvements health wise and heart wise with my blood which I don’t want to go into detail but I’d you have long covid this is worth trying as it helps break down the spike protein.” - iHerb Customer
“I am very happy with this drug! I've been drinking for two months and bought it again! My results: normalization of pressure, hemorrhoids ceased to worsen, the condition of the periarticular tissues improved. This is expressed in a decrease in stiffness and pain in the neck, knees, hands, etc. with rheumatoid arthritis. Good composition, reasonable price and a large bank. Energy has noticeably increased, no side effects are observed. The size is normal. The dosage is not too high. The benefits are obvious. The quality is top notch. Ingredients according to standards.” - iHerb Customer

Vitacost Mega Nattokinase

Image courtesy of Vitacost’s website

Vitacost is a reputable brand known for its commitment to quality, and this product is likely produced to high-quality standards. Their Mega Nattokinase supplement is said to help improve athletic performance, and it's also highly concentrated and provides 2,000 FU per capsule. It is non-GMO, vegetarian, and gluten-free.

Click here to purchase the supplement. 

Here are two public reviews:

“​​I buy this product all the time and am extremely pleased with it.” - Anonymous, Vitacost.com 
“The quality and price of this product cannot be beat. Vitacost is always ahead of the curve when it comes to providing leading edge supplements. I would recommend this product to anyone.” - LivingHealthyinFL, Vitacost.com 

Arthur Andrew Medical Nattovena Pure Nattokinase

Image courtesy of iHerb’s website

Arthur Andrew Medical Nattovena Pure Nattokinase is a double-strength nattokinase supplement that provides 4,000 FUs per capsule. Since this version is so highly concentrated, it’s important to consult your doctor and only take the product if you’re over 18. Like most nattokinase supplements, this version is vegan, gluten-free, and made with non-GMO ingredients.

Click here to buy the supplement.

Here are two public reviews:

“Got here as fast as ever. Easily one of the best between cost and quality, and in this case there is literally one other ingredient, so it's very good. The size of the pill is very reasonable and has no taste. Directions give two different protocols for dosage, going to start with the minimum and work my way to four and see if I notice any added benefits.” - iHerb Customer

“I was looking for a natural supplement for the heart and controlling blood pressure and recently discovered nattokinase. There are many options on the market but I wanted to buy one with high ratings and pure simple ingredients. This seems perfect and I was willing to pay more for my health.” - iHerb Customer 

Healthy Origins Natural Nattokinase

Image courtesy of Swanson Vitamins’ website

Healthy Origins Natural Nattokinase is designed to enhance the bioavailability of nattokinase, making it more readily absorbed by the body. This ensures that the enzyme can perform its essential functions more efficiently. You get 2,000 FUs of nattokinase per capsule, and this version is made with non-GMO ingredients. 

Click here to buy the supplement.

Here are two public reviews:

“A good addition to my regimen while appreciating quality and value.” - Patricia

“Excellent product for cardio health!” - Elvis4

Nutricost Nattokinase

Image courtesy of iHerb’s website.

Nutricost Nattokinase is meticulously crafted to ensure purity, potency, and effectiveness, making it a trusted choice for individuals looking to support their cardiovascular health naturally. This supplement is manufactured in a Good Manufacturing Practices (GMP) certified facility, ensuring that it meets strict quality and safety standards. It is free from unnecessary additives, fillers, and artificial ingredients. It contains 2,000 fibrinolytic units (FU) of nattokinase per capsule, and it's also non-GMO, gluten-free, and vegetarian-friendly.

Click here to buy the supplement.

Here are two public reviews:

“Excellent product and swift shipping. I feel this is going to be a life changing supplement.” - iHerb Customer

“A great supplement from a well-known brand. The price is optimal, the quality is top notch.” - iHerb Customer

Source Naturals NSK-SD Nattokinase

Image courtesy of iHerb’s website

Source Naturals is a well known and respected company in the field of nutrition and supplements. It comes in capsule form, which makes it easy to swallow and digest. You should take it with water before eating. Like most versions of the supplement, it offers 2000 FUs per capsule. This version is both vegetarian and vegan friendly, as well as gluten and dairy free. 

Click here to buy the supplement.

Here are two public reviews:

“Good quality branded ingredients with easy small dose size. Thumbs up!” - iHerb Customer

“It's great value for money and I like the product to improve my blood circulation and feeling better.” - iHerb Customer 

NusaPure Nattokinase

Image courtesy of Amazon’s website

NusaPure Nattokinase contains a whopping 4,000 FUs, making it more potent than the average nattokinase supplement. As such, those under 18 should not take this version, and you should consult your doctor before starting. This version is also made with high quality, pure nattokinase enzyme extract for maximum effectiveness. It’s made with non-GMO ingredients and free of additives. This supplement is also proudly manufactured in the United States in a GMP certified facility, ensuring quality and safety.

Click here to buy the supplement.

Here are two public reviews:

“Using this product has reduced my endo pain and it also lowered my blood pressure. It's an excellent addition to the other meds I take to help my endo. I have endo rupturing through my skin so I'm able to see the effects, less inflammation and pain in the area and less bleeding. There's very limited research on this for endo, but the research looked promising so I wanted to try it. I've been using this for at least a year and it's definitely improved my symptoms.” - Faith, Amazon

“Have been well pleased with the value and quality. I reorder on a very regular basis.” - Emily, Amazon

Again, it's important to consult your doctor before taking nattokinase, especially if you take bloodthinners or other cardiovascular medications that can interact with it.

Allison Radziwon

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